Month: April 2018
Fabrication of Patient-Specific Intracranial Aneurysm Models for Burst Testing
Abstract
A cerebral or intracranial aneurysm (ICA) is a condition that is defined as a local dilation of an artery in the brain due to locally weakened blood vessel walls. This creates a balloon-shaped bulge in the thin artery wall that can rupture, and the ensuing subarachnoid hemorrhage can cause a stroke, coma, or even death. Therefore, it is of interest to understand how ICAs grow and eventually rupture in order to develop earlier diagnosis or treatment techniques. Current imaging technologies include computed tomography and magnetic resonance imaging, which can be used to generate three-dimensional computer-assisted design models. However, these 3D models only provide the shape of the ICA and monitory macroscopic growth of aneurysms, but are too low resolution to determine the specific wall thickness of vasculature. Aneurysms tend to rupture at the thinnest point in the vessel wall, but it is difficult to predict rupture location from just 3D geometry alone using a CT scan reconstruction.
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Dr. Ren invited to talk at IEEE NEMS 2018
A Skull-Mounted Robot with a Compact and Lightweight Parallel Mechanism for Positioning in Minimally Invasive Neurosurgery
Abstract
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Finite Time Fault Tolerant Control for Robot Manipulators Using Time Delay Estimation and Continuous Nonsingular Fast Terminal Sliding Mode Control
Ultrasound-Assisted Guidance With Force Cues for Intravascular Interventions
Image guidance during minimally invasive intravascular interventions is primarily achieved based on X-ray fluoroscopy, which has several limitations including limited 3-D imaging capability, significant doses of radiation to operators, and lack of contact force measurement between the cardiovascular tissue and interventional tools. Ultrasound imaging can be adopted to complement or possibly replace 2-D fluoroscopy for intravascular interventions due to its portability, safety to use, and the ability of providing depth information. However, it is challenging to precisely visualize catheters and guidewires in the ultrasound images. In this paper, we propose a novel method to figure out both the position and orientation of the catheter tip in 2-D ultrasound images in real time by detecting and tracking a passive marker attached to the catheter tip. Moreover, the contact force can be estimated simultaneously as well via measuring the length variation of the marker. A geometrical model-based method is introduced to detect the initial position of the marker, and a Kanade-Lucas-Tomasi-based algorithm is developed to track the position, orientation, and length of the marker. The ex vivo experiment results validate the effectiveness of the proposed approach in automatically locating the catheter tip in ultrasound images and its capability of sensing the contact force. Therefore, it can be concluded that the presented method can be utilized to better facilitate operators during intravascular interventions.
