Tracking Magnetic Particles under Ultrasound Imaging using Contrast-Enhancing Microbubbles

Abstract

Magnetic microbubbles which can be controlled by an external magnetic field have been explored as a method for precise andย efficient drug delivery. In this paper, a technique for the fabrication of microbubble encapsulated magnetic spheres is presented. Theย resultant magnetic spheres were subsequently imaged using ultrasound and the encapsulated microbubbles proved to appear as bright spotsย and resulted in enhanced ultrasound image contrast, as compared to the solid magnetic spheres which appeared dull. A tracking algorithmย was then developed for the tracking of the magnetic microbubbles based on optical flow tracking. Further development of the magneticย microbubbles and tracking algorithm can lead to future use of the tracking algorithm in the case of in vivo injection of the magneticย microbubbles.

Publications

1. Loh Kai Ting, Ren Hongliang and Li Jun, Tracking Magnetic Particles under Ultrasound Imaging using Contrast-Enhancing Microbubbles, The 11th Asian Conference on Computer Aided Surgery, 2015.

Poster in BME Showcase 2015

KT Poster Final Printed

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