**Exciting News! 🎉**

We’re delighted to share that 6 papers from our lab have been accepted at IEEE ROBIO 2024 (https://lnkd.in/gXQYD7By)!

Our team has made significant contributions to the field of robotic surgery, with a diverse range of research topics

including:

– Neural Rendering

– Gaussian Splatting

– Registration and Reconstruction

– Augmented Reality for surgical planning and training

– Soft Continuum Robots

– Vision-guided surgery

Get a sneak peek at our digest figures below. We’ll be sharing more details soon! If you’re attending #ROBIO2024 in Bangkok,

we’d love to connect and discuss potential collaborations!

Let’s build connections and drive innovation together!

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🎉Exciting News🎉 We have made great achievements at #MICCAI2024!

Our paper entitled “LighTDiff: Surgical Endoscopic Image Low-Light Enhancement with T-Diffusion”, led by our former lab member Tong Chen, Qingcheng Lyu, and our PhD student Long Bai, has been awarded the 🎊MICCAI 2024 Best Paper Runner-Up!🎊

This is a collaborative work between the lab of Prof Luping Zhou from The University of Sydney, our #LabREN (http://www.labren.org/mm/), and Qilu Hospital of Shandong University. Congrats to all coauthors!!!

We have also ranked #2nd in the very competitive BraTS Challenge on Sub-Sahara-Africa Adult Glioma (BraTS-SSA)! Our methodology is so-called “Transferring Knowledge from High-Quality to Low-Quality MRI for Adult Glioma Diagnosis”. Stay tuned for more updates!

Congrats to Team members: Yanguang Zhao, Long Bai, Zhaoxi Zhang, and Prof Hongliang Ren from #LabREN at The Chinese University of Hong Kong, Dr. Yanan Wu from China Medical University, and Dr. Mobarakol Islam from University College London.

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Checkout our latest work published in #ARSO2024, entitled “Navigation of Tendon-driven Flexible Robotic Endoscope through Deep Reinforcement Learning”. The work was finished by Chi Kit Ng during his undergraduate study in our #LabREN and he is now continuing his research with us, awarded the scholarship of The Hong Kong PhD Fellowship Scheme (#HKPFS), the only EE awardee in this batch!

Robotic endoscopes play a crucial role in diagnosing gastrointestinal disease and performing tumor resections. While current research primarily focuses on autonomously controlling rigid robots, establishing control models for flexible robots remains challenging. To address this, model-free deep reinforcement learning (DRL) presents a promising approach for enabling agents to make decisions under uncertainty.

In this paper, we investigate the control policy of a flexible endoscope using Simulation Open Framework Architecture (SOFA) platform. We design a flexible tendon-driven robotic endoscope (TDRE) and develop a custom simulation environment within SOFA to train DRL agents. Our approach involves implementing the Proximal Policy Optimization (PPO) algorithm to approximate an optimal policy for trajectory planning. The optimal policy facilitates trajectory tracking tasks for the TDRE’s end-effector, such as circle trajectories and action disturbances, without requiring fine-tuning policy network parameters. Experimental results demonstrate that our approach achieves near real-time performance (30 FPS). The feedforward neural network of the policy provides feedback, enabling closed-loop control of TDRE. Furthermore, our experiments show that the navigation success rate of TDRE exceeds 90% within a tolerant error of 3 mm in free space. Notably, compared to direct training with contact, navigation tasks with contact retrained by a pre-trained policy in free space exhibit enhanced navigation capabilities.

Paper link: https://lnkd.in/gDH5xYA5

Co-authors: Chi Kit Ng; Huxin Gao; Tian-Ao Ren; Sam, Jiewen Lai; Hongliang Ren

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🎊 Exciting News!!!🎊

We will present 4 main conference papers and 4 workshop/challenge papers in #MICCAI2024, Marrakesh, Morocco. These cover interesting topics such as #DDPM, Low-light Image Enhancement, #GaussianSplatting, Depth Reconstruction, Data Robustness, and Medical Image Segmentation. Congrates to all of our awesome collaborators! Do drop by our poster and oral sessions if you are interested in our work!

Main Conference 1: EndoUIC: Promptable Diffusion Transformer for Unified Illumination Correction in Capsule Endoscopy

Long Bai, Oct 08, Poster Session 3, 10:30 – 11:30

Poster ID: T-AM-091

Paper: https://lnkd.in/gV5MzKct

Code: https://lnkd.in/ghYauAGM

Main Conference 2: Endo-4DGS: Endoscopic Monocular Scene Reconstruction with 4D Gaussian Splatting

YIMING HUANG, Oct 08, Poster Session 4, 15:00 – 16:30 

Post ID: T-PM-074

Paper: https://lnkd.in/gtDwbyWg

Code: https://lnkd.in/ggaDgVxW

Main Conference 3: EndoDAC: Efficient Adapting Foundation Model for Self-Supervised Depth Estimation from Any Endoscopic Camera

Beilei Cui, Oct 08, Poster Session 4, 15:00 – 16:30

Poster ID: T-PM-076

Paper: https://lnkd.in/gQgpFFpq

Code: https://lnkd.in/g_bfk56S

Main Conference 4: LighTDiff: Surgical Endoscopic Image Low-Light Enhancement with T-Diffusion

Tong Chen, Oct 09, Oral Session 16, 13:30 – 15:00, Poster Session 6, 15:00 – 16:30

Poster ID: W-PM-154

Paper: https://lnkd.in/gybFHPmu

Code: https://lnkd.in/gmmWXCnd

Workshop 1: A Review of 3D Reconstruction Techniques for Deformable Tissues in Robotic Surgery

Long Bai, Oct 06, Oral & Poster

Embodied AI and Robotics for HealTHcare (EARTH) Workshop

Paper: https://lnkd.in/gD6juYyV

Code: https://lnkd.in/gnwhzrQn

Workshop 2: Benchmarking Robustness of Endoscopic Depth Estimation with Synthetically Corrupted Data

Beilei Cui, Oct 10, Poster, 15:10 – 16:05

9th International Workshop on Simulation and Synthesis in Medical Imaging (SASHIMI)

Paper: https://lnkd.in/gnWtK37B

Code: https://lnkd.in/gjc2FBWT

Challenge 1: Transferring Knowledge from High-Quality to Low-Quality CT for Adult Glioma Diagnosis

Long Bai, Oct 06, Oral (Top-performing Team)

BraTS Challenge on Sub-Sahara-Africa Adult Glioma (BraTS-SSA)

Challenge 2: Ensembling Multi-scale Networks for Accurate Adult Glioma Diagnosis

Long Bai, Oct 06, Poster

BraTS Adult Glioma Post Treatment Challenge (BraTS-GLI)

We are thrilled to share our journal paper titled “Patient-mounted NeuroOCT for Targeted Minimally-invasive Micro-resolution Volumetric Imaging in Brain In Vivo” accepted to Advanced Intelligent Systems! In this paper, we introduce an innovative ✨ wearable neuro optical coherence tomography (neuroOCT) ✨ system, featuring a lightweight hydraulic 5-DoF skullbot combined with a neuroendoscope approximately 0.6 mm in diameter.

This system facilitates targeted, minimally invasive neuroimaging with an axial resolution of about 2.4 μm and a transverse resolution of around 4.5 μm in the deep brain in vivo. The skullbot enables precise deployment of the neuroendoscope with a targeting accuracy of ±1.5 mm transversely and ±0.25 mm longitudinally, confirmed through optical phantom studies. The skullbot can be securely attached to the head, allowing for motion-insensitive stereotactic imaging within the brain.

We validated the system’s capabilities by demonstrating targeted imaging of a tumor in a brain phantom and conducting in vivo micro-resolution volumetric neuroimaging of fine structures within a mouse brain. This advanced device offers in situ disease evaluation at a micro- resolution level and serves as a promising intraoperative imaging tool, complementing existing4 clinical whole-brain imaging modalities such as MRI.

Our findings suggest that the neuroOCT system can significantly advance minimally invasive high-resolution targeted neuroendoscopy, thereby improving patient safety during neurosurgical procedures.

The paper will be available at https://lnkd.in/gFREQFbS

Stay tuned!

This is a collabrative work between CUHK ABI Lab (https://lnkd.in/gUuzQqDt) and REN Lab (http://www.labren.org/mm/).

Congrates to authors: Chao Xu+, Zhiwei Fang+, Huxin Gao, Tinghua Zhang, Tao Zhang, Peng Liu, Hongliang Ren*, and Wu ‘Scott’ YUAN*

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✨ Boosting Robustness of Magnetic Tracking ✨

We are thrilled to share that our latest research paper “Enhancing Anti-interference of Magnetic Tracking: A MagRobustNet-based Framework with Self-supervised Anomaly Detection and Measurements Recovery” has been accepted by IEEE Transactions on Industrial Informatics!

Magnetic tracking technology often suffers from diverse and unpredictable interferences in practical applications, such as hard-/soft-iron interferences and sensor saturation, leading to reduced localization accuracy or even tracking failure.

To address these issues, we propose a MagRobustNet-based framework with anomaly detection and measurement recovery. In the first step, disjoint mask sets are used in conjunction with MagRobustNet to detect anomalous measurements subject to disturbances. In the second step, the interfered regions are masked, and MagRobustNet is applied again to recover their expected measurements from neighboring normal data.

Our proposed method not only enhances the tracking system’s anti-interference capability, but also indicates the interfered regions, offering a new potential diagnostic method for localizing ingested foreign bodies in clinical practice.

Check out our video demonstration at https://lnkd.in/g9TNnsA4

Stay tuned for the paper publication!

Congrats to all co-authors: Shijian Su, Huxin Gao, and Hongliang Ren from the Department of Electronic Engineering, The Chinese University of Hong Kong; Hai Lan and Houde Dai from Quanzhou Institute of Equipment Manufacturing, Haixi Institute, CAS.

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We are excited to share our latest research entitled “Disentangling Contact Location for Stretchable Tactile Sensors from Soft Waveguide Ultrasonic Scatter Signals” collaborated by Zhiheng Li and Yuan Lin, has been accepted by Advanced Intelligent Systems!

Flexible tactile sensors have garnered significant attention due to their flexible, lightweight, and comfortable nature, catering to the growing demands in various applications such as human-machine interfaces, healthcare, and robotics. However, it remains a challenge to achieve precise contact location sensing that is decoupled from sensor strain and touching forces. Thus, this paper proposes a novel data-driven approach for force contact location sensing (FCLS), based on scatter signals (SS) of the ultrasonic waveguide, with the influence of sensor strain and forces. This method utilizes deep CNNs to fuse local and global features of the soft waveguide ultrasonic SS and an MLP to perform regression modeling on the fused features and FCL, thereby obtaining FCL information. The experimental results indicate that the accuracy of the proposed FCLS method has an MAE loss of 0.627 mm and an MRE loss of 3.19%.

The full paper will be available at: https://lnkd.in/gKr22Uvi

Co-Authors: Zhiheng Li (CUHK), Yuan Lin (SJTU), Peter B. Shull (SJTU) and Hongliang Ren (CUHK). The first two authors contributed equally to this work.

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Revolutionizing endomicroscopy with motor-free technology! ✨

Our team has developed a telerobotic OCT endoscope that overcomes the limitations of traditional systems. This innovative device offers high-resolution imaging, reduced thermal and electrical risks, and guidewire-independent navigation. Steerable angles up to 110° and distortion-free 3D imaging in vivo demonstrate its potential for improved patient outcomes.

Abstract:

Intraluminal epithelial abnormalities, potential precursors to significant conditions like cancer, necessitate early detection for improved prognosis. We present a motor-free telerobotic optical coherence tomography (OCT) endo scope that offers high-resolution intraluminal imaging and overcomes the limitations of traditional systems in navigating curved lumens. This system incorporates a compact magnetic rotor with a rotatable diametrically magnetized cylinder permanent magnet (RDPM) and a reflector, effectively mitigating thermal and electrical risks by utilizing an external magnetic field to maintain temperature increases below 0.5°C and generated voltage under 0.02mV. Additionally, a learning-based method corrects imaging distortions resulting from nonuniform rotational speeds. Demonstrating superior maneuverability, the device achieves steerable angles up to 110° and operates effectively in vivo, providing distortion-free 3D programmable imaging in mouse colons. This advancement represents a significant step towards guidewire-independent endomicroscopy, enhancing biosafety and potential patient outcomes.

Check out our latest publication in Nature Communications: https://lnkd.in/guAazam9  

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We are excited to share our latest work, “PneumaOCT: Pneumatic optical coherence tomography endoscopy for targeted distortion-free imaging in tortuous and narrow internal lumens”, which has been published in Science Advances!!! 🎉🎉🎉

The complex anatomy of internal luminal organs, like bronchioles, poses challenges for endoscopic optical coherence tomography (OCT). These challenges include limited steerability for targeted imaging and nonuniform rotation distortion (NURD) with proximal scanning. Using rotary micromotors for distal scanning could address NURD but raises concerns about electrical safety and costs.

We present pneumaOCT, the first pneumatic OCT endoscope, comprising a steerable catheter with a soft pneumatic actuator and an imaging probe with a miniature pneumatic turbine. With a diameter of 2.8 mm, pneumaOCT allows for a bending angle of up to 237°, facilitating navigation through narrow turns. The pneumatic turbine enables adjustable imaging speeds from 51 to 446 revolutions per second. We demonstrate the pneumaOCT in vivo imaging of mouse esophagus and colon, as well as targeted and distortion-free imaging of peripheral bronchioles in a bronchial phantom and a porcine lung. This advancement substantially improves endoscopic OCT for navigational imaging in curved and narrow lumens.

In the future, we will further develop an autonomous pneumaOCT endoscopy system by integrating an automated external robotic system, navigation guidance (such as x-ray imaging or MRI), and intelligent sensing and control algorithms. This advancement will have a substantial impact on the development of robotic endoscopy techniques in complex clinical practice.

For more details, please find the paper at https://lnkd.in/gtcM7v7p

This is collaborative work between LabREN (http://www.labren.org/), ABI Lab (https://lnkd.in/gUuzQqDt) and Department of Surgery, CUHK. Congrats to all authors: Tinghua Zhang, Sishen YUAN, Chao Xu, Peng Liu, Hing-Chiu Chang, Sze Hang Calvin Ng, Hongliang Ren, and Wu ‘Scott’ YUAN.

An example application of pneumaOCT for targeted distortion-free imaging in the peripheral lung.
PneumaOCT imaging of ex vivo porcine lung.

Our latest research work titled “A Real-Time Self-Sensing Approach to Sensor Array Configuration Fusing Prior Knowledge for Reconfigurable Magnetic Tracking Systems” has been accepted by IEEE/ASME Transactions on Mechatronics!

Impact:

The reconfigurability of magnetic tracking systems (MTSs) allows for its application in workspaces of different sizes. For instance, with appropriate configuration adjustments, it can be utilized for tasks such as tongue tracking in the head, tracheal intubation navigation in the neck, and even muscle tracking in the legs and arms. However, the dynamic changes in sensor array configuration, known as deformation, caused by posture changes during long-duration examinations, impose significant challenges on MTSs that heavily rely on magnetometer poses.

Here we propose a real-time self-sensing method based on the sensor array structural model and magnetic dipole model, which simultaneously estimates the magnet pose and the hinge angles on the sensor array. The self-sensing capability opens up a new way for perceiving the morphology of origami robots and measuring the curvature of flexible catheters

Paper: https://lnkd.in/dnmcvusm

Authors: Shijian Su; Xindi Yang; Zhen Li; Hongliang Ren

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