{"id":3290,"date":"2025-08-05T04:57:36","date_gmt":"2025-08-05T04:57:36","guid":{"rendered":"http:\/\/www.labren.org\/mm\/?p=3290"},"modified":"2025-08-05T13:03:15","modified_gmt":"2025-08-05T13:03:15","slug":"we-are-thrilled-to-share-our-journal-paper-titled-patient-mounted-neurooct-for-targeted-minimally-invasive-micro-resolution-volumetric-imaging-in-brain-in-vivo-accepted-to-advanced-i","status":"publish","type":"post","link":"http:\/\/www.labren.org\/mm\/news\/we-are-thrilled-to-share-our-journal-paper-titled-patient-mounted-neurooct-for-targeted-minimally-invasive-micro-resolution-volumetric-imaging-in-brain-in-vivo-accepted-to-advanced-i\/","title":{"rendered":"We are thrilled to share our journal paper titled \u201cPatient-mounted NeuroOCT for Targeted Minimally-invasive Micro-resolution Volumetric Imaging in Brain In Vivo\u201d accepted to Advanced Intelligent Systems! In this paper, we introduce an innovative \u2728 wearable neuro optical coherence tomography (neuroOCT) \u2728 system, featuring a lightweight hydraulic 5-DoF skullbot combined with a neuroendoscope approximately 0.6 mm in diameter."},"content":{"rendered":"\n

This system facilitates targeted, minimally invasive neuroimaging with an axial resolution of about 2.4 \u03bcm and a transverse resolution of around 4.5 \u03bcm in the deep brain in vivo. The skullbot enables precise deployment of the neuroendoscope with a targeting accuracy of \u00b11.5 mm transversely and \u00b10.25 mm longitudinally, confirmed through optical phantom studies. The skullbot can be securely attached to the head, allowing for motion-insensitive stereotactic imaging within the brain.<\/p>\n\n\n\n

We validated the system’s capabilities by demonstrating targeted imaging of a tumor in a brain phantom and conducting in vivo micro-resolution volumetric neuroimaging of fine structures within a mouse brain. This advanced device offers in situ disease evaluation at a micro- resolution level and serves as a promising intraoperative imaging tool, complementing existing4 clinical whole-brain imaging modalities such as MRI.<\/p>\n\n\n\n

Our findings suggest that the neuroOCT system can significantly advance minimally invasive high-resolution targeted neuroendoscopy, thereby improving patient safety during neurosurgical procedures.<\/p>\n\n\n\n

The paper will be available at https:\/\/lnkd.in\/gFREQFbS<\/p>\n\n\n\n

Stay tuned!<\/p>\n\n\n\n

This is a collabrative work between CUHK ABI Lab (https:\/\/lnkd.in\/gUuzQqDt) and REN Lab (http:\/\/www.labren.org\/mm\/).<\/p>\n\n\n\n

Congrates to authors: Chao Xu<\/a>+, Zhiwei Fang<\/a>+, Huxin Gao<\/a>, Tinghua Zhang<\/a>, Tao Zhang, Peng Liu, Hongliang Ren<\/a>*, and Wu ‘Scott’ YUAN<\/a>*<\/p>\n\n\n\n

\"No<\/figure>\n\n\n\n
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\"No<\/figure>\n","protected":false},"excerpt":{"rendered":"

This system facilitates targeted, minimally invasive neuroimaging with an axial resolution of about 2.4 \u03bcm and a transverse resolution of around 4.5 \u03bcm in the deep brain in vivo. The skullbot enables precise deployment of the neuroendoscope with a targeting accuracy of \u00b11.5 mm transversely and \u00b10.25 mm longitudinally, confirmed\u2026 Continue reading<\/a><\/p>\n","protected":false},"author":17,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[4],"tags":[126,186,187],"class_list":["post-3290","post","type-post","status-publish","format-standard","hentry","category-news","tag-cuhk","tag-neurooct","tag-skullbot"],"_links":{"self":[{"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/posts\/3290","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/users\/17"}],"replies":[{"embeddable":true,"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/comments?post=3290"}],"version-history":[{"count":1,"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/posts\/3290\/revisions"}],"predecessor-version":[{"id":3291,"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/posts\/3290\/revisions\/3291"}],"wp:attachment":[{"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/media?parent=3290"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/categories?post=3290"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.labren.org\/mm\/wp-json\/wp\/v2\/tags?post=3290"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}